Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis

Authors

  • Ma. Melizza S. Villalon Department of Otorhinolaryngology Head and Neck Surgery Veterans Memorial Medical Center
  • Celso V. Ureta Department of Otorhinolaryngology Head and Neck Surgery Veterans Memorial Medical Center

DOI:

https://doi.org/10.32412/pjohns.v30i1.395

Keywords:

Parathyroid carcinoma, primary hyperparathyroidism

Abstract

Objective: To present a rare case of primary parathyroid carcinoma and discuss its clinical findings and management.

Methods:

Study Design:             Case Report

Setting:                        Tertiary Government Hospital

Patient:                        One

Results: A 54-year-old woman presented with a 3-year history of recurrent nephrolithiasis despite several courses of shock wave lithotripsy. She had persistent hypercalcemia and parathyroid hormone levels were noted to be elevated. Neck ultrasound showed a hypoechoic solid nodule measuring approximately 1.7 x 1.6 cm in the lateral inferoposterior aspect of the left thyroid lobe. Parathyroid scintigraphy revealed a focal uptake on the left lower thyroidal bed. The patient underwent left inferior parathyroidectomy with subtotal thyroidectomy and isthmusectomy Frozen section reported a parathyroid tumor and the final histopathologic results revealed a parathyroid carcinoma.

Conclusion: A rare case of parathyroid carcinoma was presented, manifesting with recurrent nephrolithiasis. Elevated serum calcium and intact parathyroid hormone (iPTH) can confirm a primary hyperparathyroid problem. Neck ultrasound and parathyroid scintigraphy help in the localization of a parathyroid tumor. Only final histopathologic results can confirm the diagnosis of parathyroid carcinoma. Complete surgical excision is the treatment of choice and offers a good prognosis.

Keywords: Parathyroid carcinoma, primary hyperparathyroidism

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Published

2015-06-30

How to Cite

1.
Villalon MMS, Ureta CV. Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis. Philipp J Otolaryngol Head Neck Surg [Internet]. 2015 Jun. 30 [cited 2024 May 14];30(1):54-8. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/395

Issue

Vol. 30 No. 1 (2015): Philippine Journal of Otolaryngology-Head and Neck Surgery

Section

Case Reports

License

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