Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis

Authors

  • Ma. Melizza S. Villalon Department of Otorhinolaryngology Head and Neck Surgery Veterans Memorial Medical Center
  • Celso V. Ureta Department of Otorhinolaryngology Head and Neck Surgery Veterans Memorial Medical Center

DOI:

https://doi.org/10.32412/pjohns.v30i1.395

Keywords:

Parathyroid carcinoma, primary hyperparathyroidism

Abstract

Objective: To present a rare case of primary parathyroid carcinoma and discuss its clinical findings and management.

Methods:

Study Design:             Case Report

Setting:                        Tertiary Government Hospital

Patient:                        One

Results: A 54-year-old woman presented with a 3-year history of recurrent nephrolithiasis despite several courses of shock wave lithotripsy. She had persistent hypercalcemia and parathyroid hormone levels were noted to be elevated. Neck ultrasound showed a hypoechoic solid nodule measuring approximately 1.7 x 1.6 cm in the lateral inferoposterior aspect of the left thyroid lobe. Parathyroid scintigraphy revealed a focal uptake on the left lower thyroidal bed. The patient underwent left inferior parathyroidectomy with subtotal thyroidectomy and isthmusectomy Frozen section reported a parathyroid tumor and the final histopathologic results revealed a parathyroid carcinoma.

Conclusion: A rare case of parathyroid carcinoma was presented, manifesting with recurrent nephrolithiasis. Elevated serum calcium and intact parathyroid hormone (iPTH) can confirm a primary hyperparathyroid problem. Neck ultrasound and parathyroid scintigraphy help in the localization of a parathyroid tumor. Only final histopathologic results can confirm the diagnosis of parathyroid carcinoma. Complete surgical excision is the treatment of choice and offers a good prognosis.

Keywords: Parathyroid carcinoma, primary hyperparathyroidism

Downloads

Download data is not yet available.

Downloads

Published

2015-06-30

How to Cite

1.
Villalon MMS, Ureta CV. Parathyroid Carcinoma Manifesting as Recurrent Nephrolithiasis. Philipp J Otolaryngol Head Neck Surg [Internet]. 2015 Jun. 30 [cited 2024 Nov. 21];30(1):54-8. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/395

Issue

Vol. 30 No. 1 (2015): Philippine Journal of Otolaryngology-Head and Neck Surgery

Section

Case Reports

License

Copyright transfer (all authors; where the work is not protected by a copyright act e.g. US federal employment at the time of manuscript preparation, and there is no copyright of which ownership can be transferred, a separate statement is hereby submitted by each concerned author). In consideration of the action taken by the Philippine Journal of Otolaryngology Head and Neck Surgery in reviewing and editing this manuscript, I hereby assign, transfer and convey all rights, title and interest in the work, including copyright ownership, to the Philippine Society of Otolaryngology Head and Neck Surgery, Inc. (PSOHNS) in the event that this work is published by the PSOHNS. In making this assignment of ownership, I understand that all accepted manuscripts become the permanent property of the PSOHNS and may not be published elsewhere without written permission from the PSOHNS unless shared under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.