Extramedullary Plasmacytoma in the Maxillary Sinus

Authors

  • Jennifer De Silva-Leonardo Department of Otorhinolaryngology - Head and Neck Surgery Quirino Memorial Medical Center
  • Rosario R. Bito-Ricalde Department of Otorhinolaryngology - Head and Neck Surgery Quirino Memorial Medical Center
  • Jose Roberto V. Claridad Department of Otorhinolaryngology - Head and Neck Surgery Quirino Memorial Medical Center; Department of Otorhinolaryngology - Head and Neck Surgery Far Eastern University –Nicanor Reyes Memorial Foundation Medical Center; Department of Otorhinolaryngology - Head and Neck Surgery Capitol Medical Center
  • Erasmo Gonzalo DV. Llanes Department of Otorhinolaryngology - Head and Neck Surgery Quirino Memorial Medical Center ; Department of Otorhinolaryngology College of Medicine - Philippine General Hospital University of the Philippines Manila; Department of Otorhinolaryngology - Head and Neck Surgery Rizal Medical Center

DOI:

https://doi.org/10.32412/pjohns.v24i2.683

Keywords:

Plasmacytoma, plasma cell tumor, multiple myeloma, plasma cell myeloma, extramedullary plasmacytoma

Abstract

Objective: To describe an intranasal mass initially diagnosed and treated as benign, that eventually turned out to be a malignant extramedullary plasmacytoma of the maxillary sinus, and to review the literature on its presenting signs and symptoms, diagnosis, management and pathophysiology.

Methods:

Design: Case Report 

Setting: Tertiary Public Hospital

Patient: One

Results: A 45-year-old male with persistent nasal obstruction and intermittent epistaxis underwent several biopsies of a mass shown on computed tomography scans as heterogeneously enhancing, expansile, occupying the left maxillary sinus with extension into the left nasal cavity with areas of erosion.  Immunohistochemical staining was negative for cytokeratin (CK) and leukocyte common antigen (LCA). Complete excision yielded a final histopathologic interpretation of plasmacytoma. Laboratory examinations excluded multiple myeloma. The final diagnosis was extramedullary plasmacytoma and he was treated with post-operative adjuvant radiotherapy. 

Conclusion:  Plasmacytoma may present in the sinu-nasal region and be part of a systemic disease like multiple myeloma. A high index of suspicion and thorough initial histopathological work-up may help in establishing a definitive diagnosis and providing optimum treatment.

Keywords: Plasmacytoma, plasma cell tumor, multiple myeloma, plasma cell myeloma, extramedullary plasmacytoma

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Published

2009-11-29

How to Cite

1.
De Silva-Leonardo J, Bito-Ricalde RR, Claridad JRV, Llanes EGD. Extramedullary Plasmacytoma in the Maxillary Sinus. Philipp J Otolaryngol Head Neck Surg [Internet]. 2009 Nov. 29 [cited 2024 Apr. 24];24(2):27-31. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/683

Issue

Vol. 24 No. 2 (2009): Philippine Journal of Otolaryngology-Head and Neck Surgery

Section

Case Reports

License

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