Carcinoma ex Pleomorphic Adenoma in the Parapharyngeal Space

Authors

  • Sudipta Pal Department of ENT, Head & Neck Surgery, R G Kar Medical College, Kolkata, India
  • Sampurna Pati 1Department of ENT, Head & Neck Surgery, R G Kar Medical College, Kolkata, India
  • Somnath Saha 1Department of ENT, Head & Neck Surgery, R G Kar Medical College, Kolkata, India
  • Vedula Padmini Saha Department of Plastic Surgery, R G Kar Medical College, Kolkata, India

DOI:

https://doi.org/10.32412/pjohns.v28i1.499

Keywords:

carcinoma ex pleomorphic adenoma, pleomorphic adenoma, carcinoma, parapharyngeal space, malignant transformation, minor salivary gland tumor, mandibular swing

Abstract

Objective: To present a case of carcinoma ex pleomorphic adenoma in the parapharyngeal

space and discuss its management.

 

Methods:

Design:            Case Report

Setting:           Tertiary Government Teaching Hospital

Subjects:         One

 

Results:  A 40-year-old male patient with dysphagia for three months and a left-sided mucosa-covered oropharyngeal mass was found to have a prestyloid parapharyngeal lesion on CT Scans. Fine Needle Aspiration Cytology (FNAC) revealed a pleomorphic adenoma. With a past history of parapharyngeal pleomorphic adenoma excised transorally three years before, the present mass was excised by mandibular swing approach. Post-operative recovery was uneventful, but the final histopathological report was carcinoma ex pleomorphic adenoma.

 

Conclusion: Malignant transformation should be suspected in recurrent salivary tumors in the parapharyngeal space. Provided there was truly no pre-existing malignant focus in the originally-excised tumor, and that early recurrence was not due to inadequate initial excision, this patient had a rare condition where the same tumor underwent malignant transformation within 3 years only. To the best of our knowledge, such an early transformation to malignancy of a minor salivary gland tumor of the parapharyngeal space has not been reported in the English literature.

 

Keywords: carcinoma ex pleomorphic adenoma, pleomorphic adenoma, carcinoma,  parapharyngeal space, malignant, transformation, minor salivary gland tumor,  mandibular swing

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Published

2013-06-18

How to Cite

1.
Pal S, Pati S, Saha S, Saha VP. Carcinoma ex Pleomorphic Adenoma in the Parapharyngeal Space. Philipp J Otolaryngol Head Neck Surg [Internet]. 2013 Jun. 18 [cited 2024 Nov. 8];28(1):24-7. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/499