Diagnostic-To-Treatment Interval and Disease Progression among Head and Neck Cancer Patients Undergoing Surgery

Authors

  • Gerard F. Lapiña Department of Otorhinolaryngology – Head and Neck Surgery Rizal Medical Center
  • Samantha S. Castañeda Department of Otorhinolaryngology – Head and Neck Surgery Rizal Medical Center

DOI:

https://doi.org/10.32412/pjohns.v32i1.175

Keywords:

head and neck cancer, treatment delay, diagnostic interval, tumor progression

Abstract

Objectives: To determine whether the interval from pathological diagnosis to treatment is significantly delayed, and the presence or absence of disease progression occurring in those with, and without treatment delay, among head and neck cancer patients in our institution.

Methods:

Study Design:            Retrospective Chart Review

Setting:                       Tertiary Government Hospital

Subjects: Medical records of 70 patients with newly diagnosed head and neck cancer who underwent primary surgery from January 2011 to December 2015 were retrieved and available data were extracted. 

Results:  A total of 28 patients were included in this study.  Majority of the cancers were in the larynx (42.9%) and oral cavity (42.9%).  The mean diagnostic-to-treatment interval (DTI) was 54 days, but 5(17.8%) out of the 28 had a DTI of more than 60 days. Four (80%) with a DTI more than 60 days had an upstage during surgery while 4 (17.4%) patients with DTI less than or equal to 60 days also had an upstage. 2 (60%) patients with treatment delay had tumor progression compared to 5 (21.7%) of those without treatment delay.  Only 1 (20%) out of the 5 patients with treatment delay had increased nodal metastasis in contrast to 8 (34.8%) of those who did not have treatment delay.

Conclusion:  A number of patients undergoing surgery in our institution experienced delay to initiate treatment of more than 60 days and majority of these patients were noted to have disease progression. However, even patients with treatment prior to 60 days had increases in tumor stage, which may suggest that the interval aimed for should be shorter than 60 days.

Keywords: head and neck cancer, treatment delay, diagnostic interval, tumor progression

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Published

2017-06-29

How to Cite

1.
Lapiña GF, Castañeda SS. Diagnostic-To-Treatment Interval and Disease Progression among Head and Neck Cancer Patients Undergoing Surgery. Philipp J Otolaryngol Head Neck Surg [Internet]. 2017 Jun. 29 [cited 2024 Mar. 29];32(1):33-6. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/175

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