Association of Clinicodemographic Factors and Tissue Biopsy Results Among Patients with Thyroid Nodules at the Southern Philippines Medical Center

Authors

  • Madonna L. Aujero, MD Southern Philippines Medical Center
  • John Michael P. Tagsa, MD Southern Philippines Medical Center https://orcid.org/0009-0004-6568-907X
  • Gleno Lon Q. Llamera, Jr., MD Southern Philippines Medical Center

DOI:

https://doi.org/10.32412/pjohns.v38i2.2211

Keywords:

thyroid nodules, tissue biopsy, thyroid neoplasm, fine-needle aspiration biopsy

Abstract

Objective: To compare selected clinicodemographic factors of patients with thyroid nodules who underwent thyroid surgeries with their tissue biopsy results and determine any association between clinicodemographic factors and tissue biopsy results.

Methods:
Design: Retrospective review of records
Setting: Tertiary Government Training Hospital
Participants: 251 patients with thyroid nodules

Results: Of 251 patients with thyroid nodules, the majority (218; 86.9%) were females while 33 (13.1%) were males. The average age in years was 41.5±13.3 The same population also had malignant outcomes at 79.3%. Most of the patients did not have family history of thyroid malignancy (54%) and had no palpable cervical lymph nodes at presentation (75.9%). Furthermore, there was no distant metastasis at presentation for both lungs (97.7%) and bones (98.9%). There were no significant differences in tissue biopsy results when correlated with age (df=249; t=-.144; p = .886), duration of goiter (df=249; t=-.829; p = .408), and distant metastasis at presentation for lungs (Z=-5.977; p = .052) and bones (Z=-.457; p = .648). Significant differences were only evident for clinicodemographic factors such as sex (Z=-2.570; p = .010), family history (Z=-2.239; p = .020), palpable cervical lymph nodes at presentation (Z=-5.977; p = .000), and the following comorbidities: pulmonary tuberculosis (Z=-2.388; p = .017) and bronchial asthma  (Z=-2.148; p = .032) and smoking history (Z=-3.455; p=.001). Furthermore, having no palpable cervical lymph nodes at presentation were associated with malignant tissue biopsy results (B=3.616; p=.001). Patients without palpable cervical lymph nodes at presentation were 37.204 times [OR=37.204] more likely to have benign biopsy results [95% CI: 4.705 – 294.168].

Conclusion: There are greater odds of having benign biopsy results for patients without palpable cervical lymph nodes at presentation.

Downloads

Download data is not yet available.

Downloads

Published

2023-11-20

How to Cite

1.
Aujero M, Tagsa JM, Llamera GL. Association of Clinicodemographic Factors and Tissue Biopsy Results Among Patients with Thyroid Nodules at the Southern Philippines Medical Center. Philipp J Otolaryngol Head Neck Surg [Internet]. 2023 Nov. 20 [cited 2024 Jun. 23];38(2):26. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/2211