Value of the 6-Hour Postoperative Ionized Calcium Slope in Predicting Post- Thyroidectomy Occurrence of Hypocalcemia

Authors

  • Ryan E. Cabance Department of Otolaryngology – Head & Neck Surgery Manila Central University - Filemon D. Tanchoco Medical Foundation Hospital
  • Emmanuel Tadeus S. Cruz Department of Otolaryngology – Head & Neck Surgery Manila Central University - Filemon D. Tanchoco Medical Foundation Hospital; Department of Otolaryngology – Head & Neck Surgery Quezon City General Hospital

DOI:

https://doi.org/10.32412/pjohns.v30i2.339

Keywords:

ionized calcium (iCa), hypocalcemia, thyroidectomy

Abstract

Objective: To determine the value of the 6-hour postoperative ionized Calcium (iCa) slope, versus 6-hour postoperative Calcium alone, in predicting the occurrence of hypocalcemia in patients who underwent thyroid surgery in a tertiary hospital in Metro Manila.

Methods:

Study Design:            Retrospective Cross-Sectional Study

Setting:                       Tertiary Private Hospital

Subjects:                    Pre-operative and 6-hour postoperative ionized calcium determinations were analyzed in 59 patients of the ENT-HNS department in a tertiary hospital in Metro Manila who underwent thyroid surgery from January 2009 to December 2013.

Results: The 6-hr postoperative iCa slope (difference between the pre-operative and 6-hour postoperative iCa levels) of ≥0.18 mmol/L correctly predicted 57.1% of patients who eventually developed hypocalcemia, with a specificity of 81.6%, and a positive predictive value of 63.2%. In contrast, the 6-hour postoperative iCa measurement identified only 23.8% (5 out of 21) patients who developed hypocalcemia.

Conclusion: The 6-hr postoperative iCa slope increased the probability of identifying patients who developed hypocalcemia from 23.8% to 57.1%. However, as a single determination, this may  not suffice to take the place of serial iCa measurements after thyroid surgery.

Keywords: ionized calcium (iCa), hypocalcemia, thyroidectomy

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Published

2018-11-19

How to Cite

1.
Cabance RE, Cruz ETS. Value of the 6-Hour Postoperative Ionized Calcium Slope in Predicting Post- Thyroidectomy Occurrence of Hypocalcemia. Philipp J Otolaryngol Head Neck Surg [Internet]. 2018 Nov. 19 [cited 2024 Mar. 28];30(2):13-8. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/339

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