Gastrointestinal Stromal Tumor of the Tongue

Authors

  • Andrie Jeremy Formanez Department of Otolaryngology Head and Neck Surgery Armed Forces of the Philippines Medical Center
  • Grace Naomi B. Galvan-Bravo Department of Otolaryngology Head and Neck Surgery Armed Forces of the Philippines Medical Center

DOI:

https://doi.org/10.32412/pjohns.v28i1.501

Keywords:

recurrent tongue mass, gastrointestinal stromal tumor, immunohistochemistry, c-kit tyrosine kinase inhibitor

Abstract

Objective: To report a case of a gastrointestinal stromal tumor presenting as a recurrent tongue mass

Methods:

Study Design: Case Report

Setting: Tertiary Public Hospital

Participant: One patient

Results: A 40-year-old Filipino soldier from Camarines Sur presented with a recurrent tongue mass two years after excision of a progressively-enlarging, firm, fixed, non-tender mass at the left posterior third of the tongue diagnosed as a Schwannoma. Repeat surgery involved partial glossectomy via midline mandibular swing. Final histopathologic report after immunohistochemical studies for CD117, SMA, and S100 was extraintestinal gastrointestinal stromal tumor of the tongue. The patient was started on the c-kit tyrosine kinase inhibitor Imatinib with no recurrence 10 months post treatment.

Conclusion: Gastrointestinal stromal tumor may be considered when presented with a recurrent tongue mass despite complete surgical resection. Surgical removal is curative for most lesions. Post-operative chemotherapy with the use of Imatinib is valuable.

Keywords: recurrent tongue mass, gastrointestinal stromal tumor, immunohistochemistry, c-kit tyrosine kinase inhibitor

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Published

2013-06-18

How to Cite

1.
Formanez AJ, Galvan-Bravo GNB. Gastrointestinal Stromal Tumor of the Tongue. Philipp J Otolaryngol Head Neck Surg [Internet]. 2013 Jun. 18 [cited 2025 Feb. 16];28(1):28-33. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/501

Issue

Vol. 28 No. 1 (2013): Philippine Journal of Otolaryngology-Head and Neck Surgery

Section

Case Reports

License

Copyright transfer (all authors; where the work is not protected by a copyright act e.g. US federal employment at the time of manuscript preparation, and there is no copyright of which ownership can be transferred, a separate statement is hereby submitted by each concerned author). In consideration of the action taken by the Philippine Journal of Otolaryngology Head and Neck Surgery in reviewing and editing this manuscript, I hereby assign, transfer and convey all rights, title and interest in the work, including copyright ownership, to the Philippine Society of Otolaryngology Head and Neck Surgery, Inc. (PSOHNS) in the event that this work is published by the PSOHNS. In making this assignment of ownership, I understand that all accepted manuscripts become the permanent property of the PSOHNS and may not be published elsewhere without written permission from the PSOHNS unless shared under the terms of a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license.