Primary Thyroid Lymphoma

Authors

  • Claudine Ann Musngi-Paras Department of Laboratories Philippine General Hospital University of the Philippines Manila
  • Ansarie P. Salpin Department of Laboratories Philippine General Hospital University of the Philippines Manila
  • Januario D. Veloso Department of Laboratories Philippine General Hospital University of the Philippines Manila; Department of Pathology College of Medicine University of the Philippines Manila

DOI:

https://doi.org/10.32412/pjohns.v27i1.557

Keywords:

Primary Thyroid Lymphoma, , Extranodal Marginal Zone B-cell Lymphoma, Diffuse Large B-cell Lymphoma, Claudine Ann Claudine Ann

Abstract

Eight cases of primary thyroid lymphoma were reported in a tertiary government hospital from January 2005 to August 2011. All patients presented with a diffuse enlargement of both thyroid lobes with associated obstructive symptoms. Five of these cases were extranodal marginal zone lymphoma and three were diffuse large B-cell lymphoma. Clinical features that would favor a thyroid lymphoma include tumor size of greater that 7cm, obstructive symptoms, clinical hypothyroidism or history of Hashimoto thyroiditis. Thus, these features must be considered in evaluating thyroid nodules during fine-needle aspiration biopsy. Histologically, extranodal marginal zone B-cell lymphoma shows vaguely nodular to diffuse infiltrates of small to intermediate size atypical lymphoid cells infiltrating the thyroid follicles, while diffuse large B-cell lymphoma shows sheets of large atypical lymphoid cells infiltrating the thyroid follicular epithelium.

Keywords: Primary Thyroid Lymphoma, Extranodal Marginal Zone B-cell Lymphoma, Diffuse Large B-cell Lymphoma.

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Published

2012-06-29

How to Cite

1.
Musngi-Paras CA, Salpin AP, Veloso JD. Primary Thyroid Lymphoma. Philipp J Otolaryngol Head Neck Surg [Internet]. 2012 Jun. 29 [cited 2024 Jul. 17];27(1):38-40. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/557