Oral Propranolol Therapy for Benign Capillary Hemangiomas in a Series of Adult and Pediatric Patients

Authors

  • Gerardo Aniano C. Dimaguila Department of Otolaryngology Head and Neck Surgery Pamantasan ng Lungsod ng Maynila-Ospital ng Maynila Medical Center
  • Emmanuel S. Samson Department of Otolaryngology Head and Neck Surgery Pamantasan ng Lungsod ng Maynila-Ospital ng Maynila Medical Center

DOI:

https://doi.org/10.32412/pjohns.v32i2.75

Keywords:

hemangioma, capillary, propranolol administration, oral, propranolol

Abstract

Objective: To describe outcomes of oral propranolol therapy in a series of adult and pediatric patients diagnosed with benign capillary hemangioma of the head and neck.

Methods:

            Design:           Prospective Case Series

            Setting:           Tertiary Government Hospital

Participants: Ten (10) patients representing all patients clinically diagnosed with benign capillary hemangioma of the head and neck, enrolled in the study from 2012 to 2015.

Results: Two (2) adults and eight (8) children were enrolled in the study. Although a decrease in lesion size was observed in half of the participants starting at three months, only one (1) attained complete resolution of the lesion-- a 12-year-old girl with hemangioma of the right parotid gland that attained clinical resolution of symptoms after four months of treatment. The remaining nine out of ten (9/10) participants did not attain complete clinical resolution; but there was a decrease in lesion size in four (4) of these participants. For the remaining five (5) participants, there was neither a decrease nor an increase in lesion size. Altogether, of the two adult participants, only one responded to therapy, while only 4 out of 8 pediatric participants responded to therapy. There were no noticeable differences between adult and pediatric patients in terms of resolution and plateau. Aside from mild bradycardia expected with propranolol, no adverse reactions were observed during the course of treatment.

Conclusion: Although half of our participants responded to oral propranolol therapy, whether these observations may be attributable to oral propranolol alone cannot be concluded.

Keywords: hemangioma, capillary; hemangioma; propranolol administration, oral; propranolol

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Published

2018-07-24

How to Cite

1.
Dimaguila GAC, Samson ES. Oral Propranolol Therapy for Benign Capillary Hemangiomas in a Series of Adult and Pediatric Patients. Philipp J Otolaryngol Head Neck Surg [Internet]. 2018 Jul. 24 [cited 2024 Apr. 25];32(2):34-7. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/75

Issue

Vol. 32 No. 2 (2017): Philippine Journal of Otolaryngology-Head and Neck Surgery

Section

Original Articles

License

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