Triple Primary Malignancy (Synchronous Papillary and Follicular Thyroid Carcinomas and Diffuse B-Cell Lymphoma of the Submandibular Gland and Cervical Lymph Nodes) in a 70-Year-Old Woman

Authors

DOI:

https://doi.org/10.32412/pjohns.v40i.2289

Keywords:

Multiple primary malignant tumors, follicular thyroid carcinoma, papillary thyroid carcinoma, submandibular gland diffuse b cell lymphoma

Abstract

Objective: To report a case of triple primary malignant neoplasms in a 70-year-old woman diagnosed with follicular and papillary thyroid carcinoma and diffuse B-cell lymphoma of the right submandibular gland and cervical lymph nodes.

Methods:
Design: Case Report
Setting: Tertiary Government Training Hospital
Patient: One

Results: A 70- year-old woman presented with a four-year history of gradually enlarging anterior neck mass, associated with a right submandibular mass and neck nodes for one year. The gradual progression of her symptoms made the patient think that it was a benign condition. This led to a delay in medical consultation. The patient underwent total thyroidectomy with functional neck dissection of the ipsilateral right neck. Histopathology revealed simultaneous follicular and papillary thyroid carcinoma, and diffuse B-cell lymphoma of the cervical lymph nodes. The patient was referred to medical oncology and nuclear medicine for further management.

Conclusion: Our patient was incidentally diagnosed with follicular and papillary thyroid carcinoma and diffuse B cell lymphoma of the cervical lymph nodes after surgery. Such triple primary malignant neoplasms in a single individual are rare, and as in our case, may only be diagnosed in hindsight.

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Published

2025-09-20

How to Cite

1.
Roxas AJP. Triple Primary Malignancy (Synchronous Papillary and Follicular Thyroid Carcinomas and Diffuse B-Cell Lymphoma of the Submandibular Gland and Cervical Lymph Nodes) in a 70-Year-Old Woman. Philipp J Otolaryngol Head Neck Surg [Internet]. 2025 Sep. 20 [cited 2026 May 2];:36-40. Available from: https://pjohns.pso-hns.org/index.php/pjohns/article/view/2289

Issue

Vol. 40 Supplement (2025): Philippine Journal of Otolaryngology Head and Neck Surgery

Section

Case Reports

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